9:11 AM 9/10/2020 - Blogs Review: News - coronavirus and the brain | Sexual harassment in the FBI - the hidden epidemic. What do we really know about it?
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9:11 AM 9/10/2020 - Blogs Review: News - coronavirus and the brain | Sexual harassment in the FBI - the hidden epidemic. What do we really know about it?
https://thenewsandtimes.blogspot.com/2020/09/am-9102020-blogs-review-news.html
Blogs - Links and Pages - The News and Times - Blogs by Michael Novakhov
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Blogs from Michael_Novakhov (27 sites) | |||||||
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The News And Times: 8:48 AM 9/10/2020 - Three Stages to COVID-19 Brain Damage | |||||||
8:48 AM 9/10/2020 - Three Stages to COVID-19 Brain Damagehttps://thenewsandtimes.blogspot.com/2020/09/848-am-9102020-three-stages-to-covid-19.htmlSaved and Shared Stories In 50 Posts___________________________________________Saved and Shared Stories mikenov on Twitter: Three Stages to COVID-19 Brain Damage, New Review ... coronavirus and the brain: reviews - Google Search google.com/search?q= The News And Times | |||||||
Tweets And News - From Michael Novakhov: 8:38 AM 9/10/2020 - News - coronavirus and the brain | |||||||
8:38 AM 9/10/2020 - News - coronavirus and the brain - Google Search google.com/search?q=coron pic.twitter.com/3rRHsFVcGHhttps://tweetsandnews.blogspot.com/2020/09/838-am-9102020-news-coronavirus-and.htmlMichael Novakhov - SharedNewsLinksMichael Novakhov - SharedNewsLinks | In Brief | -Michael Novakhov - SharedNewsLinks Three Stages to COVID-19 Brain Damage, New Review ... coronavirus and the Tweets And News - From Michael Novakhov | |||||||
Michael Novakhov - SharedNewsLinks: Three Stages to COVID-19 Brain Damage, New Review ... coronavirus and the brain: reviews - Google Search google.com/search?q=coron pic.twitter.com/kgEsaCUgME | |||||||
Three Stages to COVID-19 Brain Damage, New Review ... coronavirus and the brain: reviews - Google Search google.com/search?q=coron pic.twitter.com/kgEsaCUgME Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: News - coronavirus and the brain - Google Search google.com/search?q=coron pic.twitter.com/3rRHsFVcGH | |||||||
News - coronavirus and the brain - Google Search google.com/search?q=coron pic.twitter.com/3rRHsFVcGH Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: 8:09 AM 9/10/2020 - Trump administration intends to end Covid-19 screenings of passengers arriving from overseas - Saved and Shared Stories In 50 Posts | |||||||
8:09 AM 9/10/2020 - Saved and Shared Stories In 50 Posts___________________________________________
Michael Novakhov - SharedNewsLinks | |||||||
Tweets And News - From Michael Novakhov: 8:09 AM 9/10/2020 - Trump administration intends to end Covid-19 screenings of passengers arriving from overseas - Saved and Shared Stories In 50 Posts | |||||||
8:09 AM 9/10/2020 - Saved and Shared Stories In 50 Postshttps://tweetsandnews.blogspot.com/2020/09/809-am-9102020-trump-administration.html___________________________________________Saved and Shared Stories Michael Novakhov - SharedNewsLinks: 7:25 AM 9/10/2020 - Tweets: Sexual harassment in the FBI - the hidden epidemic. What do we really know about it?mikenov on Twitter: Airport coronavirus Tweets And News - From Michael Novakhov | |||||||
Michael Novakhov - SharedNewsLinks: Neuroinvasion of SARS-CoV-2 in human and mouse brain | bioRxiv | |||||||
AbstractAlthough COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects multiple organ systems including the central nervous system (CNS). Yet, there is no consensus whether the virus can infect the brain, or what the consequences of CNS infection are. Here, we used three independent approaches to probe the capacity of SARS-CoV-2 to infect the brain. First, using human brain organoids, we observed clear evidence of infection with accompanying metabolic changes in the infected and neighboring neurons. However, no evidence for the type I interferon responses was detected. We demonstrate that neuronal infection can be prevented either by blocking ACE2 with antibodies or by administering cerebrospinal fluid from a COVID-19 patient. Second, using mice overexpressing human ACE2, we demonstrate in vivo that SARS-CoV-2 neuroinvasion, but not respiratory infection, is associated with mortality. Finally, in brain autopsy from patients who died of COVID-19, we detect SARS-CoV-2 in the cortical neurons, and note pathologic features associated with infection with minimal immune cell infiltrates. These results provide evidence for the neuroinvasive capacity of SARS-CoV2, and an unexpected consequence of direct infection of neurons by SARS-CoV-2. Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: coronavirus and the brain - Google Search | |||||||
How Does Coronavirus Affect the Brain? | Johns Hopkins ...www.hopkinsmedicine.org conditions-and-diseases <a href="http://www.hopkinsmedicine.org" rel="nofollow">www.hopkinsmedicine.org</a> conditions-and-diseases Jun 4, 2020 - Q: In what ways does the coronavirus affect the brain? A: Cases around the world show that patients with COVID-19 can have a variety of ... How the Coronavirus Attacks the Brain - The New York Timeswww.nytimes.com 2020/09/09 health coronavirus-b... <a href="http://www.nytimes.com" rel="nofollow">www.nytimes.com</a> 2020/09/09 health coronavirus-b... 14 hours ago - How the Coronavirus Attacks the Brain. It's not just the lungs the pathogen may enter brain cells, causing symptoms like delirium and confusion ... From 'brain fog' to heart damage, COVID-19's lingering ...www.sciencemag.org news 2020/07 brain-fog-he... <a href="http://www.sciencemag.org" rel="nofollow">www.sciencemag.org</a> news 2020/07 brain-fog-he... Jul 31, 2020 - The list of lingering maladies from COVID-19 is longer and more varied than most doctors could have imagined. Ongoing problems include ... Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: 7:25 AM 9/10/2020 - Tweets: Sexual harassment in the FBI - the hidden epidemic. What do we really know about it? | |||||||
Michael Novakhov - SharedNewsLinks | |||||||
Tweets And News - From Michael Novakhov: 7:25 AM 9/10/2020 - Tweets: Sexual harassment in the FBI - the hidden epidemic. What do we really know about it? | |||||||
Sexual harassment in FBI - Google Search https://www.google.com/search?q=Sexual+harassment+in+FBI&newwindow=1&rlz=1C1CHBF_enUS733US733&sxsrf=ALeKk01sYUQAe3QZKY_gR2uXyQFn5-AuGg%3A1599650500769&source=lnms&tbm=nws&sa=X&ved=2ahUKEwiUsfO--tvrAhVSmVkKHVjRC7sQ_AUoAXoECBYQAw&biw=1462&bih=762&dpr=1.25 7:25 AM 9/10/2020 - Tweets by @mikenovhttps://tweetsandnews.blogspot.com/2020/09/ Tweets And News - From Michael Novakhov | |||||||
Michael Novakhov - SharedNewsLinks: itnnews's YouTube Videos: West Coast Wildfires: San Francisco's Golden Gate Bridge Covered in Dramatic Orange Haze | |||||||
Unprecedented wildfires plunged San Franciscos Bay Bridge into an apocalyptic orange glow, as a cloud of smoke covered much of California. A record 2.3 million acres have been burned this year in the state since the start of the wildfire season. Over 14,000 firefighters are battling fires in California, but blazes have been reported across the the US Pacific Northwest. #CaliforniaFires #Wildfires #SanFrancisco Report by Gianluca Avagnina. Subscribe here: http://bit.ly/ODNsubs Twitter: https://twitter.com/ODN Facebook: https://www.facebook.com/ODN/ If you wish to purchase any of our clips for commercial use, please visit: http://www.itnproductions.co.uk/news/ itnnews's YouTube Videos Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: How the Coronavirus Attacks the Brain | |||||||
The coronavirus targets the lungs foremost, but also the kidneys, liver and blood vessels. Still, about half of patients report neurological symptoms, including headaches, confusion and delirium, suggesting the virus may also attack the brain. A new study offers the first clear evidence that, in some people, the coronavirus invades brain cells, hijacking them to make copies of itself. The virus also seems to suck up all of the oxygen nearby, starving neighboring cells to death. Its unclear how the virus gets to the brain or how often it sets off this trail of destruction. Infection of the brain is likely to be rare, but some people may be susceptible because of their genetic backgrounds, a high viral load or other reasons. If the brain does become infected, it could have a lethal consequence, said Akiko Iwasaki, an immunologist at Yale University who led the work. The study was posted online on Wednesday and has not yet been vetted by experts for publication. But several researchers said it was careful and elegant, showing in multiple ways that the virus can infect brain cells. Scientists have had to rely on brain imaging and patient symptoms to infer effects on the brain, but we hadnt really seen much evidence that the virus can infect the brain, even though we knew it was a potential possibility, said Dr. Michael Zandi, consultant neurologist at the National Hospital for Neurology and Neurosurgery in Britain. This data just provides a little bit more evidence that it certainly can. Dr. Zandi and his colleagues published research in July showing that some patients with Covid-19, the illness caused by the coronavirus, develop serious neurological complications, including nerve damage. In the new study, Dr. Iwasaki and her colleagues documented brain infection in three ways: in brain tissue from a person who died of Covid-19, in a mouse model and in organoids clusters of brain cells in a lab dish meant to mimic the brains three-dimensional structure. Other pathogens including the Zika virus are known to infect brain cells. Immune cells then flood the damaged sites, trying to cleanse the brain by destroying infected cells. The coronavirus is much stealthier: It exploits the brain cells machinery to multiply, but doesnt destroy them. Instead, it chokes off oxygen to adjacent cells, causing them to wither and die. The researchers didnt find any evidence of an immune response to remedy this problem. Its kind of a silent infection, Dr. Iwasaki said. This virus has a lot of evasion mechanisms. Coronavirus Schools Briefing: Its back to school or is it? These findings are consistent with other observations in organoids infected with the coronavirus, said Alysson Muotri, a neuroscientist at the University of California, San Diego, who has also studied the Zika virus. The coronavirus seems to rapidly decrease the number of synapses, the connections between neurons. Days after infection, and we already see a dramatic reduction in the amount of synapses, Dr. Muotri said. We dont know yet if that is reversible or not. The virus infects a cell via a protein on its surface called ACE2. That protein appears throughout the body and especially in the lungs, explaining why they are favored targets of the virus. Previous studies have suggested, based on a proxy for protein levels, that the brain has very little ACE2 and is likely to be spared. But Dr. Iwasaki and her colleagues looked more closely and found that the virus could indeed enter brain cells using this doorway. Its pretty clear that it is expressed in the neurons and its required for entry, Dr. Iwasaki said. Her team then looked at two sets of mice one with the ACE2 receptor expressed only in the brain, and the other with the receptor only in the lungs. When researchers introduced the virus into these mice, the brain-infected mice rapidly lost weight and died within six days. The lung-infected mice did neither. Despite the caveats attached to mouse studies, the results still suggest that virus infection in the brain may be more lethal than respiratory infection, Dr. Iwasaki said. The virus may get to the brain through the olfactory bulb which regulates smell through the eyes or even from the bloodstream. Its unclear which route the pathogen is taking, and whether it does so often enough to explain the symptoms seen in people. I think this is a case where the scientific data is ahead of the clinical evidence, Dr. Muotri said. Researchers will need to analyze many autopsy samples to estimate how common brain infection is and whether it is present in people with milder disease or in so-called long-haulers, many of whom have a host of neurological symptoms. Forty percent to 60 percent of hospitalized Covid-19 patients experience neurological and psychiatric symptoms, said Dr. Robert Stevens, a neurologist at Johns Hopkins University. But the symptoms may not all stem from the viruss invasion of brain cells. They may be the result of pervasive inflammation throughout the body. For example, inflammation in the lungs can release molecules that make the blood sticky and clog up blood vessels, leading to strokes. Theres no need for the brain cells themselves to be infected for that to occur, Dr. Zandi said. But in some people, he added, it may be low blood oxygen from infected brain cells that leads to strokes: Different groups of patients may be affected in different ways, he said. Its quite possible that youll see a combination of both. Some cognitive symptoms, like brain fog and delirium, might be harder to pick up in patients who are sedated and on ventilators. Doctors should plan to dial down sedatives once a day, if possible, in order to assess Covid-19 patients, Dr. Stevens said. Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: 12:51 AM 9/10/2020 - Trump Nominated For Nobel Peace Prize | |||||||
12:51 AM 9/10/2020 - Trump Nominated For Nobel Peace Prizehttps://thenewsandtimes.blogspot.com/2020/09/1251-am-9102020-trump-nominated-for.html Michael Novakhov - SharedNewsLinks
Michael Novakhov - SharedNewsLinks | |||||||
The News And Times: 12:51 AM 9/10/2020 - Trump Nominated For Nobel Peace Prize | |||||||
12:51 AM 9/10/2020 - Trump Nominated For Nobel Peace Prizehttps://thenewsandtimes.blogspot.com/2020/09/1251-am-9102020-trump-nominated-for.htmlMichael Novakhov - SharedNewsLinks All Saved Stories- 25 -Saved Stories - None "us national security" - Google News: Live Covid-19 News Updates - The New York TimesFoxNewsChannel's YouTube Videos: Tucker: President Trump wants US troops out of the Middle The News And Times | |||||||
Michael Novakhov - SharedNewsLinks: Former DNI Dan Coats thinks Putin has Trump blackmail: Woodward book | |||||||
Dan Coats, the former top intelligence official under President Donald Trump, harbored a "secret belief" that Russian President Vladimir Putin had kompromat on Trump, the veteran journalist Bob Woodward wrote in his book "Rage." The book is set to be released next Tuesday, but CNN obtained an early copy and published excerpts this week. Coats was the director of national intelligence from January 2017 to July 2019. In his book, Woodward wrote that Coats "continued to harbor the secret belief, one that had grown rather than lessened, although unsupported by intelligence proof, that Putin had something on Trump." "How else to explain the president's behavior?" Woodward wrote, according to CNN. "Coats could see no other explanation." Coats and senior staffers in his office "examined the intelligence as carefully as possible," Woodward wrote. But Coats was still uneasy about Trump and Putin's relationship. He "saw how extraordinary it was for the president's top intelligence official to harbor such deep suspicions about the president's relationship with Putin," Woodward wrote. "But he could not shake them." "Rage" is Woodward's second book about the Trump administration; he also wrote the 2018 bestseller "Fear: Trump in the White House." The president has railed against "Rage," calling it fake news and saying Woodward didn't conduct any interviews with him ahead of the book's release. For his second book about the administration, Woodward did 18 extensive interviews with the president from December 5 to July 21, according to CNN. Woodward recorded the interviews with Trump's permission, and CNN obtained copies of some of the tapes. Still, Trump said in a tweet last month that the book was "a FAKE, as always, just as many of the others have been." Coats a former Republican senator from Indiana and other senior national security officials, like former Defense Secretary James Mattis, discussed whether they needed to take "collective action" to speak out against Trump, Woodward wrote, according to CNN. Mattis resigned in late 2018 after Trump decided to pull US troops out of Syria, telling Woodward he decided to leave "when I was basically directed to do something that I thought went beyond stupid to felony stupid." The US intelligence community determined in early 2017 that Russia interfered in the 2016 presidential election to propel Trump to the Oval Office. Coats and other intelligence officials testified to Congress last year that Russia was one of the biggest national security threats facing the US ahead of the 2020 election and that it would continue employing the tactics it used in 2016 and during the 2018 midterm elections. The intelligence community also said last month that both Russia and China were attempting to interfere in this year's election and that Russia wanted Joe Biden, the Democratic nominee, to lose, while China wanted him to win. "We assess that Russia is using a range of measures to primarily denigrate former Vice President Biden and what it sees as an anti-Russia 'establishment,'" William Evanina, the director of the National Counterintelligence and Security Center, said in a statement. "This is consistent with Moscow's public criticism of him when he was Vice President for his role in the Obama Administration's policies on Ukraine and its support for the anti-Putin opposition inside Russia." Trump, meanwhile, has consistently refused to explicitly condemn Russia for its actions. His 2016 campaign derided the CIA after it concluded that year that Russia meddled in the election to help Trump. He also repeatedly criticized and attempted to thwart the FBI's investigation into Russia's interference, describing it as a "hoax" designed to undermine his presidency, even as several high profile figures in his inner circle pleaded guilty to or were convicted of crimes stemming from the probe. In 2018, during a joint press conference with Putin following a bilateral summit in Helsinki, Trump publicly sided with the Russian leader over the US intelligence community, saying, "I don't see any reason why it would be" Russia that meddled in the 2016 election. The president later walked back his comments after facing swift public backlash. John Bolton, Trump's former national security adviser, told Insider in an interview last month that the president's comments during the Helsinki summit were the most shocking and disappointing he'd heard throughout his tenure. "I was sitting in the audience with Chief of Staff John Kelly, and we were both frozen to our chairs," Bolton told Business Insider. "We couldn't believe what we had heard. And we spent a good part of the flight on Air Force One back to Washington trying to explain to the president why he was getting such a negative reaction from the press back in Washington. The president didn't seem to understand that people might be upset that he equated what Putin said with what our intelligence community said." Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: Former Spy Chief Believes Putin Had Something on Trump - 'He's Dangerous. He's Unfit' | |||||||
Former director of national intelligence Dan Coats could not shake his deep suspicions that Russian President Vladimir Putin had something on President Trump, seeing no other explanation for the presidents behavior, according to Bob Woodwards new book Rage.Coats was the presidents top intelligence official from March 2017 until August 2019. Woodward reports that Coats and his staff examined the intelligence regarding Trumps ties to Russia as carefully as possible and that he still questions the relationship between Trump and Putin despite the apparent absence of intelligence proof. But Coats was still uneasy about the relationship between Trump and Putin. He saw how extraordinary it was for the presidents top intelligence official to harbor such deep suspicions about the presidents relationship with Putin. But he could not shake them. The New York Times Michael Schmidt reported in his new book that former Deputy Attorney General Rod Rosenstein secretly curtailed an FBI counterintelligence probe into Trumps ties to Russia, meaning the full scope of decades of the presidents personal and financial dealings there has never been explored. The explosive Woodward book, which is based in part on 18 interviews that Trump sat for with the veteran journalist, details the tortured tenure of Coats and other officials described by the Washington Post as so-called adults of the Trump orbit including former Defense Secretary James Mattis and former Secretary of State Rex Tillerson. At one point, Mattis went to Washington National Cathedral to pray for the countrys fate under Trumps leadership. He reportedly told Coats, There may come a time when we have to take collective action to speak out against Trump because he is dangerous. Hes unfit. In a later conversation reported by Woodward, Mattis told Coats, The president has no moral compass. Coats reportedly responded, True. To him, a lie is not a lie. Its just what he thinks. He doesnt know the difference between the truth and a lie. The US intelligence community determined in early 2017 that Russia interfered in the 2016 presidential election to propel Trump to the Oval Office. Coats and other intelligence officials testified to Congress last year that Russia was one of the biggest national security threats facing the US ahead of the 2020 election and that it would continue employing the tactics it used in 2016 and during the 2018 midterm elections. Trump is angered by the release of the Woodward book. The Bob Woodward book will be a FAKE, as always, just as many of the others have been, Trump tweeted on Aug. 14, before the book had come out. This is despite the fact that the president sat for 18 interviews with Woodward. ON TAPE: Trump Admits To Woodward He 'Downplayed' Coronavirus With American PeoplePresident Trump admitted he knew weeks before the first confirmed US coronavirus death that the virus was dangerous, airborne, highly contagious and "more deadly than even your strenuous flus," and that he repeatedly played it down publicly. "This is deadly stuff," Trump told legendary journalist Bob Woodward on February 7. September 9, 2020 In "2020" Dan Coats Out As Intelligence Director - Trump Defender Ratcliffe NominatedPresident Trump announced on Twitter today that he will nominate Rep. John Ratcliffe (R-Texas) to replace Dan Coats as director of national intelligence. Coats, one of the reasonable voices left in the Trump cabinet, will leave office on August 15. Coats had rankled Trump more than once with his public July 28, 2019 In "Headlines" FIRST SECURITY: Trump Pushed CIA To Give Taliban Intelligence To KremlinWhy would the Russian government think it could get away with paying bounties to the Taliban to kill American soldiers? One answer to that question may be the extraordinary response that Moscow received when the Trump administration learned of a precursor to the bounty operation. From mid-2017 and into 2018, July 8, 2020 In "Foreign Affairs" Michael Novakhov - SharedNewsLinks | |||||||
Michael Novakhov - SharedNewsLinks: 6:57 AM 9/9/2020 - Today's Topics: Are California fires premeditated arsons? | |||||||
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