"Our new preprint where we show that SARS-CoV-2 VOCs are able to infect mice" | The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice - bioRxiv | Sars-cov-2 in animals | Wild rodent secondary reservoirs of sars-cov-2

"Our new preprint where we show that SARS-CoV-2 VOCs are able to infect mice" | The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice - bioRxiv | Sars-cov-2 in animals | Wild rodent secondary reservoirs of sars-cov-2

RT @YourDailyCurse: @mikenov twitter.com/ArisKatzouraki… by elalege (YourDailyCurse)
Monday March 22nd, 2021 at 4:54 AM

Mikenov On Twitter
1 Share

@mikenov twitter.com/ArisKatzouraki…

Very interesting thread on the work from @SimonLoriereLab & coworkers on the possibility of extension of the host range of P1 & B1351 to rodents. twitter.com/SimonLoriereLa…

Posted by  Aris Katzourakis 💙 (ArisKatzourakis) on Saturday, March 20th, 2021 9:38pm


14 likes, 3 retweets
Posted by  elalege (YourDailyCurse) on Sunday, March 21st, 2021 9:40am
Retweeted by  Michael Novakhov (mikenov) on Monday, March 22nd, 2021 8:15am


1 retweet

RT @SimonLoriereLab: Our new preprint where we show that SARS-CoV-2 VOCs are able to infect mice is out. Collaborative work @institutpasteu… by EtienneSimon-Loriere (SimonLoriereLab)
Monday March 22nd, 2021 at 4:54 AM

Mikenov On Twitter
1 Share

Our new preprint where we show that SARS-CoV-2 VOCs are able to infect mice is out. Collaborative work @institutpasteur *not peer reviewed yet*, short 🧵
biorxiv.org/cgi/content/sh… 1/9

Posted by  EtienneSimon-Loriere (SimonLoriereLab) on Friday, March 19th, 2021 10:21am
Retweeted by  Michael Novakhov (mikenov) on Monday, March 22nd, 2021 8:27am


742 likes, 314 retweets

sars-cov-2 in rodents - Google Search google.com/search?q=sars-… npr.org/sections/goats… by Michael Novakhov (mikenov)
Monday March 22nd, 2021 at 4:54 AM

Mikenov On Twitter
1 Share

sars-cov-2 in rodents - Google Search google.com/search?q=sars-… npr.org/sections/goats…

Posted by  Michael Novakhov (mikenov) on Monday, March 22nd, 2021 8:45am

sars-cov-2 in rats and mice - Google Search google.com/search?q=sars-… news-medical.net/news/20210308/… by Michael Novakhov (mikenov)
Monday March 22nd, 2021 at 4:54 AM

Mikenov On Twitter
1 Share

sars-cov-2 in rats and mice - Google Search google.com/search?q=sars-… news-medical.net/news/20210308/…

Posted by  Michael Novakhov (mikenov) on Monday, March 22nd, 2021 8:51am

sars-cov-2 in animals - Google Search
Monday March 22nd, 2021 at 4:37 AM

1 Share

SARS-CoV-2 in animals | American Veterinary Medical ...

www.avma.org › sars-cov-2-animals-including-pets
<a href="http://www.avma.org" rel="nofollow">www.avma.org</a> › sars-cov-2-animals-including-pets
Mar 2, 2021 — Clinical signs of SARS-CoV-2 infection in cats and dogs · Fever · Coughing · Difficulty breathing or shortness of breath · Lethargy · Sneezing · Nasal ...

COVID-19 and Animals | CDC

www.cdc.gov › 2019-ncov › daily-life-coping › animals
<a href="http://www.cdc.gov" rel="nofollow">www.cdc.gov</a> › 2019-ncov › daily-life-coping › animals
Feb 10, 2021 — Animals that can be infected with the virus that causes COVID-19 · A small number of pet cats and dogs have been reported to be infected with ...
‎Evaluation for SARS-CoV-2... · ‎If You Have Pets · ‎Confirmation of COVID-19 in...

wild rodent secondary reservoirs of sars-cov-2 - Google Search
Monday March 22nd, 2021 at 4:36 AM

1 Share

Web results


SARS-CoV-2 infection, neuropathogenesis and transmission ...

www.ncbi.nlm.nih.gov › pmc › articles › PMC7418741
<a href="http://www.ncbi.nlm.nih.gov" rel="nofollow">www.ncbi.nlm.nih.gov</a> › pmc › articles › PMC7418741
by A Fagre · Cited by 11 — Dromedary camels, which are secondary reservoirs of MERS-CoV-2, had ... suggesting that sustained transmission among wild deer mice is ...
‎Abstract · ‎Results · ‎Discussion · ‎Methods
Next Page of Stories
Loading...
Page 2

capacity of SARS-CoV-2 VOCs to infect mice - Google Search
Monday March 22nd, 2021 at 4:35 AM

1 Share

The B1.351 and P.1 variants extend SARS-CoV-2 ... - bioRxiv

www.biorxiv.org › content
<a href="http://www.biorxiv.org" rel="nofollow">www.biorxiv.org</a> › content
3 days ago — The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice ... factors are involved in the capacity of SARS-CoV-2 VOCs to infect mice.

The B1.351 and P.1 variants extend SARS-CoV-2 ... - bioRxiv

www.biorxiv.org › content
<a href="http://www.biorxiv.org" rel="nofollow">www.biorxiv.org</a> › content
3 days ago — ... although differences between viral lineages suggest that other factors are involved in the capacity of SARS-CoV-2 VOCs to infect mice.

Estimated transmissibility and impact of SARS-CoV-2 lineage ...

science.sciencemag.org › 2021/03/03 › science.abg3055
<a href="http://science.sciencemag.org" rel="nofollow">science.sciencemag.org</a> › 2021/03/03 › science.abg3055
by NG Davies · 2021 · Cited by 16 — A novel SARS-CoV-2 variant, VOC 202012/01 (lineage B.1.1.7), ... comprises roughly 95% of new SARS-CoV-2 infections in England, ... VOC 202012/01 appears unmatched in its ability to outcompete other SARS-CoV-2 lineages in England. ... Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine ...

SARS-CoV-2 variants and ending the COVID-19 pandemic ...

www.thelancet.com › PIIS0140-6736(21)00370-6 › fulltext
<a href="http://www.thelancet.com" rel="nofollow">www.thelancet.com</a> › PIIS0140-6736(21)00370-6 › fulltext
by A Fontanet · Cited by 11 — The COVID-19 pandemic has devastated health-care systems, shut down ... to protect against infection or disease from these new SARS-CoV-2 variants. ... to help develop expertise and capacity as well as strengthen health systems. ... (AZD1222) vaccine against SARS-CoV-2 VOC 202012/01 (B.1.1.7).

The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice | bioRxiv
Monday March 22nd, 2021 at 4:28 AM

1 Share

The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice

Xavier Montagutelli, Matthieu Prot, Laurine Levillayer, Eduard Baquero Salazar, Grégory Jouvion, Laurine Conquet, Flora Donati, Mélanie Albert, Fabiana Gambaro, Sylvie Behillil, Vincent Enouf, Dominique Rousset, Jean Jaubert, Felix Rey, Sylvie van der Werf, Etienne Simon-Loriere
doi: <a href="https://doi.org/10.1101/2021.03.18.436013" rel="nofollow">https://doi.org/10.1101/2021.03.18.436013</a>
This article is a preprint and has not been certified by peer review [what does this mean?].

Abstract

Receptor recognition is a major determinant of viral host range, as well as infectivity and pathogenesis. Emergences have been associated with serendipitous events of adaptation upon encounters with a novel host, and the high mutation rate of RNA viruses has been proposed to explain their frequent host shifts 1. SARS-CoV-2 extensive circulation in humans has been associated with the emergence of variants, including variants of concern (VOCs) with diverse mutations in the spike and increased transmissibility or immune escape 2. Here we show that unlike the initial virus, VOCs are able to infect common laboratory mice, replicating to high titers in the lungs. This host range expansion is explained in part by the acquisition of changes at key positions of the receptor binding domain that enable binding to the mouse angiotensin-converting enzyme 2 (ACE2) cellular receptor, although differences between viral lineages suggest that other factors are involved in the capacity of SARS-CoV-2 VOCs to infect mice. This abrogation of the species barrier raises the possibility of wild rodent secondary reservoirs and provides new experimental models to study disease pathophysiology and countermeasures.

Comments

Post a Comment

Popular posts from this blog

1:38 PM 10/6/2020 - Major hurricane brews in Gulf of Mexico, threatens Louisiana, Florida | Hopes of a ceasefire fading in Nagorno-Karabakh amid flare-up of violence

Image
1:38 PM 10/6/2020 -  Major hurricane brews in Gulf of Mexico, threatens Louisiana, Florida Hopes of a ceasefire fading in Nagorno-Karabakh amid flare-up of violence A Harvard professor has claimed, without providing a single shred of evidence, that Russian intelligence agents were able to gain access to Walter Reed hospital where President Trump recovered from coronavirus over the weekend. New Mexico Democrat Starred in Pornos Saved Stories and Video News Review Saved Stories  |  Page  |  Links  |   News Playlist on YouTube     Saved Stories  |  Page  |  Links __________________________________________________ Saved Stories - None   Нагорный Карабах: новое наступление Snorkeling in Puerto Rico Trumps covid-19 diagnosis gives him one last chance to reset his campaign Суд оправдал нового премьера Киргизии, сидевшего за захват заложника Россия Армения: экономическая игра в одни ворота ОЗХО подтвердила отравление Навального "Новичком" Major hurricane brews in Gulf of Mexico, thr
Read more

Ukraine threatens to break off diplomatic contact with Russia - Selected Articles Review - 8:30 AM 2/22/2022

Image
What is on the line for Biden if Russia invades Ukraine posted at 13:20:03 UTC by  CNN   via   CNN CNN global affairs analyst Susan Glasser and senior political analyst John Avlon discuss what is at stake for President Joe Biden if Russia decides to invade Ukraine. #CNN #News  Ukraine threatens to break off diplomatic contact with Russia Post Link Russia News  |  Russia Video News  |  Russia, Ukraine, Nato  |  Russian New York  |  All Articles  |  Current News  |  Selected Articles  |  All Current Articles Headlines  |  Video News  |  Audio News  |   Blogs  |  Sites   Michael Novakhov's favorite articles on Inoreader U.S. claims Russia has list of Ukrainians 'to be killed or sent to camps' following a military occupation - The Washington Post Ukraine threatens to break off diplomatic contact with Russia Sanctions: UK sanctions five Russian banks and predicts 'pariah status' for Putin if he takes further action against Ukraine Why Has the U.S. Sanctioned Russia in th
Read more

1:43 PM 2/3/2021 - Эхо Москвы - Особое мнение : Глеб Павловский | Scientists explain why the new Covid-19 variants could be more infectious

Image
1:43 PM 2/3/2021 Эхо Москвы - Особое мнение : Глеб Павловский podcasts.google.com/feed/aHR0cDovL… posted at 18:22:04 UTC by Michael Novakhov   via   Tweets by ‎@mikenov Эхо Москвы - Особое мнение : Глеб Павловский  podcasts.google.com/feed/aHR0cDovL…   Michael Novakhov's favorite articles on  Inoreader Michael Novakhov retweeted: Scientists explain why the new Covid-19 variants could be more infectious. This article is free to read. posted at 17:22:28 UTC by The Wall Street Journal   via   Tweets by ‎@mikenov Michael Novakhov  retweeted: Scientists explain why the new Covid-19 variants could be more infectious. This article is free to read. Michael Novakhov retweeted: "Pro-Russian lawmakers protest ban of TV channels while West welcomes it" This was a strong step by @ZelenskyyUa against Russian disinformation warfare. Ukraine is in war with Russia & needs to defend itself against its enemy, while traitors oppose. kyivpost.com/ukraine-politi… posted at 17:22:28 UTC by 
Read more

CIA Director Gina Haspel: Trump's Behavior After Election Loss Was 'Insanity' | #TNT #News #Times #US #ODNI #CIA #DOJ #FBI #Psychology of #Politics, #Intelligence, & #SecurityServices The News And Times | The FBI News Review https://shar.es/aW6eFD

Image
#TNT #News #Times #US #ODNI #CIA #DOJ #FBI #Psychology of #Politics , #Intelligence , & #SecurityServices FBI News Review https://t.co/GygPMTXODG | https://t.co/ajNK041Gy2 https://t.co/Ua2bBpRAnt https://t.co/l1zr8xU503 https://t.co/lTq00FfFv8 | https://t.co/UsVuFKTAVR pic.twitter.com/TmyNxFzknT — Michael Novakhov (@mikenov) September 26, 2021 - Post Link Tweets  by  ‎@mikenov  Michael Novakhov Retweeted On this day in History @onthisdayinhis9 # OnThisDay in History |September 21| 1985: 36 years ago: American CIA case officer Edward Lee Howard flees to Russia after being identified as a KGB agent. # OnThisDay # History # CIA # KGB # USA # Russia # EdwardLeeHoward Sep 21, 2021    Michael Novakhov Retweeted SPIES&VESPERS @SpiesVespers # OTD Sept 18,1909 legendary # CIA officer # Richard_Bissell_Jr born.Headed projects like # U2 spy plane & # Bay_of_Pigs . Sep 18, 2021    Michael Novakhov Retweeted TAYPE International @taypeinternat https://
Read more

Intelligence Operations | Abwehr and Psychoanalysis - Tweets Review | US "Psychoanalysts", many of them German Jewish charlatans, SPIED ON THEIR PATIENTS to find out the roots of TOTALITARIANISM!

Image
  Tweets   by  ‎@mikenov   Post Link   Michael Novakhov @mikenov intelligence operations - Google Search https:// shar.es/aW6YR7   10 m   Michael Novakhov @mikenov TNT # TNT # News # Times US # US ODNI # ODNI CIA # CIA DOJ # DOJ FBI # FBI # Psychology of # Politics , # Intelligence , & # SecurityServices intelligence operations - GS https:// shar.es/aW6YR7   - https:// shar.es/aW6YQe   Intelligence Operations Understanding Data, Tools, People, and Proces 10 m   Michael Novakhov @mikenov FBI # FBI Psychiatry # Psychiatry https:// twitter.com/mikenov/status /1442095222218006529  … https://twitter.com/mikenov/status/1442095222218006529 28 m   Michael Novakhov @mikenov TNT # TNT # News # Times US # US ODNI # ODNI CIA # CIA DOJ # DOJ FBI # FBI # Psychology of # Politics , # Intelligence , & # SecurityServices https:// shar.es/aW6Yze   the construction and normalization of this limited set of values actually promoted conformity and thwarted individua
Read more

@SecondGentleman Are you behind the attempts to unseat Chris Wray of the FBI? Do you plot to rule America behind the scenes? What are your relations with the Intelligence Services, including the Mossad, KGB, BND, and the New Abwehr?#FBI #NEWS #KamalaHarris THE FBI NEWS REVIEW

Image
@SecondGentleman Are you behind the attempts to unseat Chris Wray of the FBI? Do you plot to rule America behind the scenes? What are your relations with the Intelligence Services, including the Mossad, KGB, BND, and the New Abwehr? #FBI #NEWS #KamalaHarris THE FBI NEWS REVIEW pic.twitter.com/iXjNBQckgW — Michael Novakhov (@mikenov) September 22, 2021 7:29 AM 9/22/2021 - Post Link - Tweets   by  ‎@mikenov  Michael Novakhov Retweeted Milo™ @chasbottom How soon did the # FBI , # DOJ , # NYTimes , # WaPo know that the Alpha-Bank story was a @ HillaryClinton created hoax? https://twitter.com/thehill/status/1440568059211644936 4 h    Michael Novakhov Retweeted That's Enough (Anti-war Coalition) @Thatsenough0 # News : # FBI Director Wray warned that # Taliban takeover in # Afghanistan could inspire a new wave of extremism in the U.S. Wray testified before Committee that extremist groups have never stop plotting attacks on U.S. soil. https:// thatsenough.info/?p=7822   Wray
Read more

Among Those Who Marched Into the Capitol on Jan. 6: An F.B.I. Informant - The New York Times

Image
  Among Those Who Marched Into the Capitol on Jan. 6: An F.B.I. Informant - The New York Times Post Link Michael Novakhov's favorite articles on  Inoreader Видео | Эхо Москвы: Военная тайна. Зачем встретились начальники штабов России и США? [Видео] posted at 11:26:52 UTC by  info@echo.msk.ru (Эхо Москвы)   via   1. Russian Opposition from Michael_Novakhov (75 sites)  Видео | Эхо Москвы How Elizabeth Holmes sidelined the real scientists at Theranos - The Verge posted at 11:27:09 UTC   via   Top Stories - Google News How Elizabeth Holmes sidelined the real scientists at Theranos   The Verge Former Theranos Lab Director Testifies in Elizabeth Holmes Fraud Trial   NBC Bay Area Ex-Theranos Lab Director Recalls Elizabeth Holmes 'Trembling' When Confronted Over Junk Lab Tests   The Daily Beast Making Elizabeth Holmes' cringey texts public is the ultimate crime deterrent   The Verge Former employees and patients testify in Elizabeth Holmes trial   CNBC Television View Full Cov
Read more

US-American psychoanalytic community began to collaborate with the US-Intelligence Community (IC) ... psychohistorical studies on Adolf Hitler... history & consequences of this rather unexpected liaison. Psychoanalytic & the U.S. Intelligence Communities: 1940–1945

Image
Michael Novakhov's favorite articles on   Inoreader   Post Link Michael Novakhov  @mikenov posted at 09:46:05 UTC by  Michael Novakhov   via   Tweets by ‎@mikenov US-American psychoanalytic community began to collaborate with the US-Intelligence Community (IC) ... psychohistorical studies on Adolf Hitler... history & consequences of this rather unexpected liaison. Psychoanalytic & the U.S. Intel Community 1940–1945   shar.es/aW6C2X Michael Novakhov  @mikenov posted at 09:46:05 UTC by  Michael Novakhov   via   Tweets by ‎@mikenov #FBI  FBI US psychoanalytic community began to collaborate with the US-Intelligence Community (IC) ... psychohistorical studies on Adolf Hitler... history & consequences of this rather unexpected liaison. Psychoanalytic & the U.S. Intel Community 1940–1945  shar.es/aW6C2X Michael Novakhov  @mikenov posted at 10:14:41 UTC by  Michael Novakhov   via   Tweets by ‎@mikenov Another FBI director finds himself in a political vise  politi.co/3krzUE
Read more

9:12 AM 9/21/2021 - #CI (Attention, #CounterIntelligence!!!) Clearly, this is the vicious, targeted political attack on #ChrisWray, & it is orchestrated by Kamala Harris #VPHarris to control FBI #FBI. She is the agent of "#ProgressiveLeft", & also of the #NewAbwehr-#KGB, I think.

Image
9:12 AM 9/21/2021 -  Post Link -  Tweets   by  ‎@mikenov Michael Novakhov @mikenov CI Clearly, this is the vicious, targeted political attack on # ChrisWray , & it is orchestrated by Kamala Harris # VPHarris to control FBI # FBI . She is agent of " # ProgressiveLeft ", & also of # NewAbwehr - # KGB , I think. chris wray - GS https:// shar.es/aWGjOk   https://www. thenation.com/article/politi cs/wray-fbi-nassar/  … There’s No Good Reason FBI Director Chris Wray Still Has a Job Wray has a pattern of refusing to pursue powerful men like Brett Kavanaugh and Larry Nassar on behalf of women and people of color. thenation.com 4 m   Michael Novakhov @mikenov KAMALA HARRIS # FBI # NEWS FBI CI # TNT - http:// thenewsandtimes.blogspot.com   | http:// fbinewsreview.blogspot.com   # IMPEACH # KAMALAHARRIS FOR THE # ATTEMPTED COUP D'ETAT!!! Investigate this # NewAbwehr - # KGB # Trojan in depth! https:// shar.es/aWG4nN   GS - https:// shar.es/aWGjie   https://w
Read more